ActivitiesAssociate Professor Kamijo has developed a new method for modifying a carbon chain, and it has been published in Angewandte Chemie – International Edition (IF=11.709). 2016.11.24


Associate Professor Shin Kamijo (tenure track) at the Graduate School of Sciences and Technology for Innovation (Chemistry Field) has developed a method for modifying a carbon chain in a simple manner, which have been difficult to convert so far, and the research results have been published in Angewandte Chemie – International Edition (IF=11.709).


 Almost everything that enriches our lives, for example, pharmaceuticals and polymers such as plastics and nylon, and in recent years, electronic materials for organics, is produced from raw materials such as petroleum, alcohol, etc. that can be obtained from nature by making adept use of “synthetic organic chemistry.” Writing about it like this, it may seem that synthetic organic chemistry is all‐purpose. However, looking at it at the molecular level, in fact, only limited parts can be converted. However, in order to obtain specific compounds, it is necessary to convert targeted parts. With compounds for which those methods have not yet been developed, there had been problems in that even if they were synthesized, there would be many impurities, and it was difficult to obtain the target substances. One of these parts is a carbon chain in which many carbon atoms are bonded together.

 Associate Professor Kamijo has developed a method for producing aldehyde equivalents with high accuracy by means of simple operations that only consist of adding aromatic ketones to a carbon chain as reaction accelerators and making two kinds of raw materials react under optical illumination. Aldehydes that can be obtained from equivalents are known to show a variety of reactivities, so they are extremely useful compounds in synthetic chemistry. In other words, this research has succeeded in developing a new method for converting inexpensive raw materials into more valuable materials through a short process.

The molecular conversion tool which has been successfully developed this time is a totally brand new type that had not existed in the past. Therefore, it will not only make it possible to produce high value-added materials using a small number of processes, but it is also anticipated that it will bring about a paradigm shift in the way useful materials are produced. In the future, there is a possibility that it will prove useful in the efficient synthesis of pharmaceuticals and the rapid development of new chemicals that will also be effective against resistant bacteria. With regard to his ambitions for the future, Associate Professor Kamijo says he hopes to continue to take on challenges toward the development of synthetic organic chemistry tools for freely converting parts that it has hitherto not been possible to convert.